Oral ulcers caused by hydroxyurea.

Abstract

We present a case of oral ulceration in a patient with essential thrombocythaemia, that proved to be secondary to treatment with hydroxyurea. This complication has not yet been reported in the ENT literature. Hydroxyurea should be considered as a possible cause of persistent oral ulceration in patients with haematological conditions. It should be noted that the onset of this complication is not related to the dose and duration of therapy.

• Authors: V Paleri, L Lindsey
• Journal: The Journal of laryngology and otology (J Laryngol Otol) Vol. 114 Issue 12 Pg. 976-7 (Dec 2000) ISSN: 0022-2151 [Print] England
• PMID: 11177373 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Nucleic Acid Synthesis Inhibitors
• Hydroxyurea

Topics

• Aged
• Anemia (chemically induced)
• Humans
• Hydroxyurea (adverse effects)
• Male
• Mouth Mucosa
• Nucleic Acid Synthesis Inhibitors (adverse effects)
• Oral Ulcer (chemically induced)
• Stomatitis (chemically induced)
• Thrombocytosis (drug therapy)