Abstract |
The purpose of this study was to investigate how age at and value of the plateau of vital capacity (VC plateau) correlate with the severity of the progression of spinal deformity in patients with Duchenne muscular dystrophy (DMD). Changes in spinal deformity and pulmonary function in 36 DMD patients were examined in a retrospective longitudinal study. Patterns of progression of spinal deformity were classified into three types according to Oda's classification. Of the 32 patients who showed spinal deformity, six were classified as type 1, 19 as type 2, and seven as type 3. The correlation between the patterns of progression of spinal deformity and the VC plateau was examined using a discriminant analysis. Rapid and severe progression of spinal deformity could be expected in patients whose VC plateau was less than 1,900 mL and in those in which it occurred before age 14 years. Thus VC plateau may be an indicator of the severity of the progression of spinal deformity in DMD patients.
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Authors | T Yamashita, K Kanaya, K Yokogushi, Y Ishikawa, R Minami |
Journal | Journal of pediatric orthopedics
(J Pediatr Orthop)
2001 Jan-Feb
Vol. 21
Issue 1
Pg. 113-6
ISSN: 0271-6798 [Print] United States |
PMID | 11176364
(Publication Type: Journal Article)
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Topics |
- Adolescent
- Child
- Child, Preschool
- Discriminant Analysis
- Disease Progression
- Humans
- Kyphosis
(diagnostic imaging, etiology, physiopathology)
- Longitudinal Studies
- Male
- Muscular Dystrophy, Duchenne
(complications, physiopathology)
- Radiography
- Retrospective Studies
- Scoliosis
(diagnostic imaging, etiology, physiopathology)
- Vital Capacity
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