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Serum levels of N2, N2-dimethylguanosine and pseudouridine as determined by radioimmunoassay for patients with malignancy.

Abstract
A sensitive, rapid, and specific radioimmunoassay procedure was used to determine levels of N2,N2-dimethylguanosine and pseudouridine in sera of patients with acute leukemia and breast cancer. Elevated levels of both nucleosides were above standard deviations of the normal mean for patients in both disease categories.
AuthorsL Levine, T P Waalkes, L Stolbach
JournalJournal of the National Cancer Institute (J Natl Cancer Inst) Vol. 54 Issue 2 Pg. 341-3 (Feb 1975) ISSN: 0027-8874 [Print] United States
PMID1117461 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Guanosine
  • Pseudouridine
  • N(2),N(2)-dimethylguanosine
  • Uridine
Topics
  • Antibody Specificity
  • Breast Neoplasms (blood)
  • Guanosine (analogs & derivatives, blood)
  • Humans
  • Leukemia (blood)
  • Methylation
  • Neoplasms (blood)
  • Pseudouridine (blood)
  • Radioimmunoassay
  • Uridine (analogs & derivatives)

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