[Diuretic renography in the diagnostic approach of prenatal hydronephrosis].

Abstract

OBJECTIVE:

To verify the utility of diuretic renography using 99mTc-MAG3 in the evaluation of the urinary tract obstruction in patients with prenatal diagnosis of hydronephrosis. In a neonate with upper urinary tract dilatation, it is difficult to differentiate a true obstruction from a dilated non-obstructed system.

MATERIAL AND METHODS:

The retrospective study (january 1993-december 1998) included 40 consecutive patients selected from 181 newborns with a prenatal diagnosis of hydronephrosis. The mean age of the performance of the first renography was 2.6 months.

RESULTS:

The final diagnosis (once the vesicoureteral reflux was ruled out) was: ureteropelvic junction obstruction (UPJ) 16, megaureter 15, ureterocele 3 and stasis 6. Conservative treatment was applied in most of the patients. Nevertheless, 17 of them needed surgical treatment due to the high risk of the permanent renal damage.

CONCLUSIONS:

1) UPJ is the most frequent cause of neonatal hydronephrosis (NH) and consequently, of the request for diuretic renographies. The renography with 99mTc-MAG3 has the greatest influence in the therapeutic decision (identifying who should be operated on and when this should be done), due to the fact that it is the disease with the highest rate of surgical interventions. 2). The surgical indication in NH is based on the diuretic renography parameters and/or on the presence of symptomatology. In our series of surgical patients, none of those who had a differential renal function <20% with regard to the contralateral one showed recuperation after surgery (control 6 months later).

• Authors: J Cortés Hernández, J I Alonso Colmenares, S Alvarez Ruiz, E Rodeño Ortiz de Zárate, B Orive Olondriz, A M Gonzalo, P Alcorta Armentia
• Journal: Revista espanola de medicina nuclear (Rev Esp Med Nucl) Vol. 19 Issue 7 Pg. 467-71 (Dec 2000) ISSN: 0212-6982 [Print] Spain
• Vernacular Title: El renograma diurético en la estrategia diagnóstica de la hidronefrosis prenatal.
• PMID: 11171502 (Publication Type: Journal Article)

Topics

• Diuresis
• Female
• Humans
• Hydronephrosis (diagnostic imaging)
• Infant, Newborn
• Male
• Pregnancy
• Prenatal Diagnosis
• Radioisotope Renography
• Retrospective Studies