Abstract | OBJECTIVES: The primary objective of this prospective, open, non controlled, multicenter study was to collect data on migraine patient's health related quality of life before and after treatment of their migraine attacks b naratriptan orl 2.5 mg over a 12 week period. METHODS: The impact on health related quality of life was evaluated by the mean change from pre-treatment scores on the French migraine health related quality of life specific questionnaire (QVM). RESULTS: 244 patients have been included in the study. A statistically significant score improvement in health related quality of life, as measured by the global score and the four scores related to the four dimensions of the QVM questionnaire (functional, psychological, social and therapeutic) was observed compared to the pre-treatment score values. At the end of the treatment period, 67% of patients preferred naratriptan oral 2.5 mg to their usual treatment. CONCLUSION: Those data suggest that the use of naratriptan oral 2.5 mg for the treatment of migraine attacks during a 12 week period may be associated with a significant improvement in migraine patient's quality of life.
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Authors | H Massiou, C Valette, Groupe d'investigateurs de l'étude qualité de vie et naratriptan oral 2,5 mg NARF4004 |
Journal | Presse medicale (Paris, France : 1983)
(Presse Med)
Vol. 29
Issue 38
Pg. 2087-91
(Dec 09 2000)
ISSN: 0755-4982 [Print] France |
Vernacular Title | Qualité de vie des patients migraineux après traitement par naratriptan oral 2,5 mg. |
PMID | 11147046
(Publication Type: Clinical Trial, Journal Article, Multicenter Study)
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Chemical References |
- Indoles
- Piperidines
- Tryptamines
- Vasoconstrictor Agents
- naratriptan
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Topics |
- Administration, Oral
- Adult
- Female
- Humans
- Indoles
(pharmacology, therapeutic use)
- Male
- Middle Aged
- Migraine Disorders
(drug therapy, psychology)
- Piperidines
(pharmacology, therapeutic use)
- Quality of Life
- Treatment Outcome
- Tryptamines
- Vasoconstrictor Agents
(pharmacology, therapeutic use)
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