Abstract |
The objective of this article is to review the literature regarding the risk of sudden infant death syndrome ( SIDS) in bottle-fed infants compared to those that are breastfed. A meta-analysis and qualitative literature review were performed. Cohort and case-control studies were included if they met a minimum SIDS definition and presented data allowing calculation of an odds ratio (OR). Twenty-three studies were included in the meta-analysis. The studies were heterogeneous, and a majority (14) were of "fair" or "poor" quality. Crude ORs from 19 individual studies favored breastfeeding as protective against SIDS. The combined analysis indicated that bottle-fed infants were twice as likely to die from SIDS (pooled OR = 2.11; 95% CI 1.66-2.68). The results of the analysis show that there is an association between bottle-feeding and SIDS, but this may be related to confounding variables.
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Authors | K L McVea, P D Turner, D K Peppler |
Journal | Journal of human lactation : official journal of International Lactation Consultant Association
(J Hum Lact)
Vol. 16
Issue 1
Pg. 13-20
(Feb 2000)
ISSN: 0890-3344 [Print] United States |
PMID | 11138219
(Publication Type: Journal Article, Meta-Analysis, Research Support, Non-U.S. Gov't)
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Topics |
- Bottle Feeding
(adverse effects, statistics & numerical data)
- Breast Feeding
(statistics & numerical data)
- Case-Control Studies
- Child, Preschool
- Cohort Studies
- Confounding Factors, Epidemiologic
- Humans
- Infant
- Infant, Newborn
- Odds Ratio
- Research Design
- Risk Factors
- Sudden Infant Death
(epidemiology, etiology, prevention & control)
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