Conservation of small-airway function by tacrolimus/cyclosporine conversion in the management of bronchiolitis obliterans following lung transplantation.

Abstract	We studied serial lung function in 11 patients with bronchiolitis obliterans syndrome who were treated with tacrolimus conversion following lung or heart-lung transplantation. Our results show that tacrolimus conversion slows the decline of lung function in bronchiolitis obliterans syndrome. The attenuation continues for at least 1 year following conversion.
Authors	M P Revell, M E Lewis, C G Llewellyn-Jones, I C Wilson, R S Bonser
Journal	The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation (J Heart Lung Transplant) Vol. 19 Issue 12 Pg. 1219-23 (Dec 2000) ISSN: 1053-2498 [Print] United States
PMID	11124493 (Publication Type: Journal Article)
Chemical References	Immunosuppressive Agents Cyclosporine Tacrolimus
Topics	Biopsy Bronchi (physiopathology) Bronchiolitis Obliterans (drug therapy) Cyclosporine (therapeutic use) Disease Progression Follow-Up Studies Forced Expiratory Volume (drug effects) Heart-Lung Transplantation (physiology) Humans Immunosuppressive Agents (therapeutic use) Lung Transplantation (physiology) Maximal Midexpiratory Flow Rate (drug effects) Retrospective Studies Spirometry Statistics, Nonparametric Syndrome Tacrolimus (therapeutic use)

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