[Medicinal plant preparations used as adjuvant therapeutics in experimental oncology].

Abstract

Experiments on mice inoculated with metastasing Lewis lung carcinoma showed that the antitumor and antimetastatic effects of cyclophosphan (cyclophosphamide) are potentiated by the extracts of phytopreparations based on Baikal scullcap (Scutellaria baikalensis), rhodiola (Rhodiola rosea), common licorice (Glycyrrhiza glabra), and their principal acting components--baikalin, paratyrosol, and glycyrram.

• Authors: T G Razina, E P Zueva, E N Amosova, S G Krylova
• Journal: Eksperimental'naia i klinicheskaia farmakologiia (Eksp Klin Farmakol) 2000 Sep-Oct Vol. 63 Issue 5 Pg. 59-61 ISSN: 0869-2092 [Print] Russia (Federation)
• Vernacular Title: Preparaty iz lekarstvennykh rasteniĭ kak sredstva dopolnitel'noĭ terapii v éksperimental'noĭ onkologii.
• PMID: 11109531 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antineoplastic Agents
• Flavonoids
• Plant Extracts
• 4-hydroxyphenylethanol
• baicalin
• Cyclophosphamide
• Phenylethyl Alcohol
• Glycyrrhetinic Acid

Topics

• Animals
• Antineoplastic Agents (therapeutic use)
• Carcinoma, Lewis Lung (drug therapy)
• Cyclophosphamide (therapeutic use)
• Drug Therapy, Combination
• Female
• Flavonoids (therapeutic use)
• Glycyrrhetinic Acid (therapeutic use)
• Male
• Mice
• Mice, Inbred C57BL
• Phenylethyl Alcohol (analogs & derivatives, therapeutic use)
• Plant Extracts (therapeutic use)
• Xenograft Model Antitumor Assays