Perspectives on modern orthopaedics: use of Adcon-L for epidural scar prevention.

Abstract

Adcon-L is a biodegradable gel matrix that was recently approved by the Food and Drug Administration for use during single-level posterior lumbar laminectomy or laminotomy procedures. Experimental and clinical studies have suggested that the use of this product will decrease postoperative epidural scarring. However, the relationship between epidural fibrosis and patient outcome remains unclear. If the treating surgeon is of the opinion that there is a need to reduce epidural scar, the use of this product appears worthwhile. However, further studies are needed to evaluate clinical outcome and justify the use of this product on a routine basis.

• Authors: J S Fischgrund
• Journal: The Journal of the American Academy of Orthopaedic Surgeons (J Am Acad Orthop Surg) 2000 Nov-Dec Vol. 8 Issue 6 Pg. 339-43 ISSN: 1067-151X [Print] United States
• PMID: 11104397 (Publication Type: Journal Article, Review)

Chemical References

• ADCON-L
• Gels
• Organic Chemicals

Topics

• Animals
• Cicatrix (prevention & control)
• Gels (therapeutic use)
• Humans
• Laminectomy
• Organic Chemicals