Abstract |
Based on the known anti- metastasis activities of lactosides and galactosides, a galactosyl and a lactosyl trimannoside were prepared via the conventional Koenigs-Knorr and trichloroacetimidate methods, respectively. Through typical deblocking procedures, a tetrasaccharide alpha-D-Galp-(1 --> 2)-alpha-D-Manp-(1 --> 2)-alpha-D-Manp-(1 --> 6)-alpha-D-ManpOCH3 and a pentasaccharide beta-D-Galp-(1 --> 4)-beta-D-Glcp-(1 --> 2)-alpha-D-Manp-(1 --> 2)-alpha-D-Manp-(1 --> 6)-alpha-D-ManpOCH3 were obtained.
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Authors | H Li, Q Li, M S Cai, Z J Li |
Journal | Carbohydrate research
(Carbohydr Res)
Vol. 328
Issue 4
Pg. 611-5
(Oct 06 2000)
ISSN: 0008-6215 [Print] Netherlands |
PMID | 11093718
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antineoplastic Agents
- Galactosides
- Glycosides
- Mannosides
- Oligosaccharides
- lactosides
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Topics |
- Antineoplastic Agents
(chemical synthesis)
- Carbohydrate Conformation
- Carbohydrate Sequence
- Galactosides
(chemical synthesis)
- Glycosides
(chemical synthesis)
- Mannosides
(chemistry)
- Molecular Sequence Data
- Neoplasm Metastasis
(prevention & control)
- Oligosaccharides
(chemical synthesis, chemistry)
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