| Abstract | From 1998 to 2000, we performed neoadjuvant intra-arterial infusion chemotherapy using docetaxel (60 mg/m2) a few times with 5 patients with local advanced breast cancer and inflammatory breast cancer. Therapeutic effects included 3 cases of PR among the breast tumor patients and downstaging was obtained 2 cases. No critical side effects were found due to this chemotherapy. We could perform mastectomy in all the cases. We consider intra-arterial infusion using docetaxel to be highly effective with few side effects in cases of advanced breast cancer. |
| Authors | K Doi, T Ohchi, S Kudo, M Takahashi, T Sakamoto, T Ochiai, T Sakae, A Ishihara
(Affiliation: Dept. of Surgery, Miyazaki Prefectural Nobeoka Hospital.)
|
| Journal | Gan to kagaku ryoho. Cancer & chemotherapy
(Gan To Kagaku Ryoho)
Vol. 27
Issue 12
Pg. 1823-5
(Oct 2000)
ISSN: 0385-0684 JAPAN |
| PMID | 11086421
(Publication Type: Clinical Trial, English Abstract, Journal Article)
|
| Chemical References |
- Antineoplastic Agents, Phytogenic
- Taxoids
- docetaxel
- Paclitaxel
|
| Topics |
- Adenocarcinoma
(drug therapy)
- Adult
- Antineoplastic Agents, Phytogenic
(therapeutic use)
- Breast Neoplasms
(drug therapy, pathology)
- Chemotherapy, Cancer, Regional Perfusion
- Drug Administration Schedule
- Female
- Humans
- Infusions, Intra-Arterial
- Middle Aged
- Neoadjuvant Therapy
- Paclitaxel
(analogs & derivatives, therapeutic use)
- Taxoids
|
