Treatment of giant cell granuloma of the maxilla with intralesional injection of steroids.

Abstract

BACKGROUND:

Giant cell granuloma is rare in the head and neck region and most commonly affects the maxilla and mandible. Although it is a benign disease process, it may be locally destructive. Surgery is the treatment currently recommended. Because of the location of the disease, surgery may be disfiguring. Because it is a benign process, less radical nonsurgical treatment alternatives are desirable.

METHODS:

A case report of a giant cell granuloma treated with steroid injections.

RESULTS:

After six weekly intralesional steroid injections, a giant cell granuloma of the maxilla became calcified and smaller. After a follow-up period of 2 years, there was no evidence of regrowth, and the bony osteolytic lesion had filled with bone. A review of the literature revealed two case reports of successful steroid injections with similar response.

CONCLUSIONS:

Steroid injections are a viable alternative in the treatment of giant cell granuloma, which may avoid surgery.

• Authors: A Khafif, G Krempl, J E Medina
• Journal: Head & neck (Head Neck) Vol. 22 Issue 8 Pg. 822-5 (Dec 2000) ISSN: 1043-3074 [Print] United States
• PMID: 11084644 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glucocorticoids
• Triamcinolone
• Bupivacaine

Topics

• Adult
• Bupivacaine (administration & dosage)
• Female
• Follow-Up Studies
• Glucocorticoids (administration & dosage)
• Granuloma, Giant Cell (diagnosis, drug therapy)
• Humans
• Injections, Intralesional
• Maxillary Neoplasms (diagnosis, drug therapy)
• Tomography, X-Ray Computed
• Treatment Outcome
• Triamcinolone (administration & dosage)