Abstract | PURPOSE: METHODS: Three children with CAH and suboptimal response to medical management underwent bilateral laparoscopic adrenalectomy. Parents were counseled extensively regarding the experimental nature of this treatment and the potential long-term complications. RESULTS: All children recovered quickly after a mean hospital stay of 1.8 days. Pathologic examination of the removed adrenal glands showed persistent cortical hyperplasia. Follow-up at 6 months indicated marked reduction in abnormal androgen production, which allowed lowering of the steroid dosing to physiologic levels. CONCLUSION: In children with CAH refractory to medical management, bilateral laparoscopic adrenalectomy can be performed safely with almost trivial morbidity. Although early results are very encouraging, the anticipated long-term beneficial effects on growth, short stature, and adult infertility will require years to assess.
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Authors | R L Meyers, J R Grua |
Journal | Journal of pediatric surgery
(J Pediatr Surg)
Vol. 35
Issue 11
Pg. 1586-90
(Nov 2000)
ISSN: 0022-3468 [Print] United States |
PMID | 11083429
(Publication Type: Case Reports, Journal Article)
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Topics |
- Adrenal Hyperplasia, Congenital
(diagnosis, surgery)
- Adrenalectomy
(methods)
- Child
- Child, Preschool
- Female
- Follow-Up Studies
- Humans
- Laparoscopy
(methods)
- Male
- Minimally Invasive Surgical Procedures
(methods)
- Sensitivity and Specificity
- Severity of Illness Index
- Treatment Outcome
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