[Intrauterine therapy with levonorgestrel releasing IUD of women with hypermenorrhea secondary to uterine fibroids].

Abstract

OBJECTIVES:

The aim of the study was to evaluate the effectiveness of Mirena IUD (Schering) treatment in women with severe menstrual bleedings secondary to uterine fibroids.

MATERIAL AND METHODS:

The study comprised 12 women in the age of 30 to 43 years (average 36.4) with uterine fibroids and severe menstrual bleedings. Eight patients developed anemia with hemoglobin levels below 12 g/dL. All women were treated with the levonorgestrel releasing IUD. Half of the group was observed for 6, and the remaining women for 12 months. Intensity of menstrual bleedings was evaluated prior and after the treatment. US evaluation comprised measurements of endometrium and the fibroids.

RESULTS:

No early complications were observed following the insertion of the IUD. Six weeks following the insertion, one patient had persisted menstrual bleedings and was operated, the remaining 11 noted decrease in the intensity of menstruation. After twelve weeks 3 out of 6 women with intramural fibroids developed ammenorrhea, the remaining 3 had scanty menstrual bleedings. Hemoglobin levels were normal in 11 women already 6 months after the insertion of IUD. Post treatment US revealed endometrium thickness of no more then 4 mm, and no change in the fibroids volume.

CONCLUSION:

Insertion of levonorgestrel releasing Mirena IUD (Schering) reduces intensity of menstrual bleedings secondary to uterine fibroids.

• Authors: A Starczewski, M Iwanicki
• Journal: Ginekologia polska (Ginekol Pol) Vol. 71 Issue 9 Pg. 1221-5 (Sep 2000) ISSN: 0017-0011 [Print] Poland
• Vernacular Title: Wewnatrzmaciczna terapia levonorgestrelem obfitych miesiaczek spowodowanych mieśniakami macicy--doniesienie wstepne.
• PMID: 11083008 (Publication Type: English Abstract, Journal Article)

Chemical References

• Contraceptives, Oral, Synthetic
• Levonorgestrel

Topics

• Adult
• Contraceptives, Oral, Synthetic (administration & dosage, therapeutic use)
• Drug Administration Routes
• Female
• Humans
• Intrauterine Devices, Medicated
• Leiomyoma (complications)
• Levonorgestrel (administration & dosage, therapeutic use)
• Menorrhagia (drug therapy, etiology)
• Uterine Neoplasms (complications)