Laparoscopy with ultrasonographic guidance of intraamniotic methotrexate injection for ectopic pregnancy. A report of two cases.

Abstract

BACKGROUND:

The efficacy of laparoscopic intratubal injection of methotrexate is reportedly controversial.

CASES:

A 29-year-old woman with an interstitial-isthmic pregnancy and a 30-year-old woman with an ampullary pregnancy surrounded by dense adhesions were treated with intraamniotic injection of methotrexate with ultrasonographically guided laparoscopy (LUS). The ectopic pregnancies resolved quickly, without further intervention. The human chorionic gonadotropin concentrations were negligible by 18 and 25 days.

CONCLUSION:

Intraamniotic methotrexate injection with LUS is an effective treatment for unruptured interstitial and tubal pregnancies in patients with dense adhesions.

• Authors: S Akira, T Ishihara, A Yamanaka, T Takeshita, H Kaseki, T Araki
• Journal: The Journal of reproductive medicine (J Reprod Med) Vol. 45 Issue 10 Pg. 844-6 (Oct 2000) ISSN: 0024-7758 [Print] United States
• PMID: 11077636 (Publication Type: Case Reports, Journal Article)

Chemical References

• Abortifacient Agents, Nonsteroidal
• Methotrexate

Topics

• Abortifacient Agents, Nonsteroidal (administration & dosage)
• Adult
• Female
• Humans
• Injections, Intralesional
• Laparoscopy (methods)
• Methotrexate (administration & dosage)
• Pregnancy
• Pregnancy, Ectopic (diagnostic imaging, prevention & control, surgery)
• Ultrasonography