Abstract | BACKGROUND: METHODS: RESULTS: We found two psychiatric patients, one male and one female, with decreased porphobilinogen deaminase activity. When the families of these patients were studied, one brother was found to have an abnormality. Among controls, a woman was found to have the abnormality and her father was found to have typical features of the disease. CONCLUSIONS: These results indicate a prevalence of porphyria in Mexican psychiatric patients similar to controls, and that measurement of PBG deaminase activity is a good tool for defining acute intermittent porphyria carriers.
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Authors | A Jara-Prado, P Yescas, F J Sánchez, C Ríos, R Garnica, E Alonso |
Journal | Archives of medical research
(Arch Med Res)
2000 Jul-Aug
Vol. 31
Issue 4
Pg. 404-8
ISSN: 0188-4409 [Print] United States |
PMID | 11068084
(Publication Type: Journal Article)
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Chemical References |
- Hydroxymethylbilane Synthase
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Topics |
- Acute Disease
- Adolescent
- Adult
- Aged
- Alcoholism
(blood, complications, enzymology)
- Borderline Personality Disorder
(blood, complications, enzymology)
- Depression
(blood, complications, enzymology)
- Female
- Humans
- Hydroxymethylbilane Synthase
(blood)
- Male
- Mexico
(epidemiology)
- Middle Aged
- Pedigree
- Personality Disorders
(blood, complications, enzymology)
- Porphyria, Acute Intermittent
(blood, complications, enzymology, epidemiology)
- Prevalence
- Schizophrenia, Paranoid
(blood, complications, enzymology)
- Suicide, Attempted
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