Detection of hepatitis G virus (HGV) RNA and antibodies to the HGV envelope protein E2 in a cohort of hemodialysis patients.

Abstract

An analysis of the evolution of hepatitis G virus (HGV) infection markers was performed for a cohort of 58 hemodialyzed patients. During follow-up (4.88 +/- 0.42 years), a group of these patients cleared their antibodies against the envelope protein E2 with (4 of 29 cases; 13.8%) or without (9 of 29 cases; 31%) the reappearance of viremia. This finding implies a temporally limited protection in patients previously infected with HGV.

• Authors: T Pérez-Gracia, F Galán, J A Girón-González, A Lozano, B Benavides, E Fernández, M Rodríguez-Iglesias
• Journal: Journal of clinical microbiology (J Clin Microbiol) Vol. 38 Issue 11 Pg. 4277-9 (Nov 2000) ISSN: 0095-1137 [Print] United States
• PMID: 11060111 (Publication Type: Journal Article)

Chemical References

• Hepatitis Antibodies
• RNA, Viral
• Viral Envelope Proteins
• glycoprotein E2, GB virus C

Topics

• Adult
• Aged
• Cohort Studies
• Female
• Flaviviridae (immunology, isolation & purification, physiology)
• Hepatitis Antibodies (blood)
• Hepatitis, Viral, Human (diagnosis, virology)
• Humans
• Male
• Middle Aged
• Prospective Studies
• RNA, Viral (blood)
• Renal Dialysis
• Viral Envelope Proteins (immunology)
• Viremia