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Antiretroviral therapy of HIV-1 infection: established treatment strategies and new therapeutic options.

Abstract
Recently, studies have shown that non-nucleoside reverse transcriptase inhibitors, such as efavirenz or nevirapine, in combination with two nucleoside analogues have an antiretroviral potency comparable to protease inhibitor containing regimens. Triple combination therapy that includes a non-nucleoside reverse transcriptase inhibitor can therefore be regarded as an effective alternative first-line treatment of HIV-1 infection.
AuthorsG R Kaufmann, D A Cooper
JournalCurrent opinion in microbiology (Curr Opin Microbiol) Vol. 3 Issue 5 Pg. 508-14 (Oct 2000) ISSN: 1369-5274 [Print] England
PMID11050451 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
Chemical References
  • Anti-HIV Agents
  • HIV Protease Inhibitors
  • Reverse Transcriptase Inhibitors
Topics
  • Anti-HIV Agents (therapeutic use)
  • Antiretroviral Therapy, Highly Active
  • HIV Infections (drug therapy)
  • HIV Protease Inhibitors (therapeutic use)
  • HIV-1
  • Humans
  • Reverse Transcriptase Inhibitors (therapeutic use)
  • Salvage Therapy

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