Abstract | BACKGROUND:
Frey syndrome was first described by Baillarger in 1853. Frey provided a detailed analysis and description as " auriculotemporal syndrome" in 1923. According to the literature, even the most recent therapeutic measures described for the treatment of patients with Frey syndrome have little chance of success and a high incidence of side effects. Thus, a type of treatment is desirable that can suppress the symptoms of Frey syndrome and can offer a good success rate, minimum invasiveness, and few side effects. METHODS: The experience of the authors and data from the literature confirmed the efficacy of type A botulinum toxin treatment for patients with Frey syndrome up to a maximum observation period of 3 years. RESULTS: In the current study, seven patients with severe, symptomatic Frey syndrome after parotidectomy were treated successfully with type A botulinum toxin. CONCLUSIONS: The method of local, intracutaneous treatment with type A botulinum toxin for patients with Frey syndrome is effective, virtually side-effect free, and minimally invasive.
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Authors | J J von Lindern, B Niederhagen, S Bergé, G Hägler, R H Reich |
Journal | Cancer
(Cancer)
Vol. 89
Issue 8
Pg. 1659-63
(Oct 15 2000)
ISSN: 0008-543X [Print] United States |
PMID | 11042557
(Publication Type: Journal Article)
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Copyright | Copyright 2000 American Cancer Society. |
Chemical References |
- Neuromuscular Agents
- Botulinum Toxins, Type A
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Topics |
- Adult
- Botulinum Toxins, Type A
(administration & dosage, therapeutic use)
- Female
- Humans
- Injections, Intradermal
- Male
- Middle Aged
- Neuromuscular Agents
(administration & dosage, therapeutic use)
- Parotid Neoplasms
(complications, surgery)
- Sweating, Gustatory
(drug therapy)
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