| Abstract | Four hundred patients with painful muscle spasm caused by five common musculoskeletal diseases were included in a double-blind controlled trial of chlormezanone, orphenadrine, orphenadrine/paracetomol and placebo. Patients were treated for one week and then asked for their subjective assessment of the treatment. Fifty-three per cent improved on placebo, 57 percent on chlormezanone, 66 percent on orphenadrine and 71 percent on orphenadrine/paracetamol. There was no significant difference between chlormezanone and placebo, but orphenadrine appeared to have a beneficial effect, presumably because of its muscle relaxant activity. |
| Authors | E J Valtonen |
| Journal | Annals of clinical research
(Ann Clin Res)
Vol. 7
Issue 2
Pg. 85-8
(Apr 1975)
ISSN: 0003-4762 FINLAND |
| PMID | 1103709
(Publication Type: Clinical Trial, Controlled Clinical Trial, Journal Article, Randomized Controlled Trial)
|
| Chemical References |
- Placebos
- Acetaminophen
- Chlormezanone
- Orphenadrine
|
| Topics |
- Acetaminophen
(therapeutic use)
- Chlormezanone
(therapeutic use)
- Clinical Trials as Topic
- Drug Evaluation
- Drug Therapy, Combination
- Humans
- Muscle Cramp
(drug therapy)
- Orphenadrine
(therapeutic use)
- Placebos
|
