HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Serum alhpa 1-acid glycoprotein concentrations in healthy and tumor-bearing cats.

Abstract
The purpose of this study was to evaluate alpha 1-acid glycoprotein (AGP) concentrations in tumor-bearing and healthy cats. The hypothesis of the present study was that AGP concentrations would be significantly increased in tumor-bearing cats. Serum from 51 healthy and 97 tumor-bearing, client-owned cats was harvested at the time of presentation and stored at -80 degrees C until assayed. Cats with measurable, histologically confirmed malignancies, and healthy cats of similar ages were included. Serum was assayed for AGP concentration by using a radial immunodiffusion method. AGP concentrations were significantly (P = .0051) higher in tumor-bearing (763 +/- 595 microg/mL; mean +/- SD) when compared to healthy cats (501 +/- 377 microg/mL; mean +/- SD). Of the tumor-bearing cats, 35 had carcinomas, 33 had sarcomas, and 26 had discrete, round cell tumors. AGP concentrations were 645 +/- 62 microg/mL, 660 +/- 540 microg/mL, and 967 +/- 860 microg/mL, respectively, and there were no significant differences among the groups.
AuthorsK A Selting, G K Ogilvie, S E Lana, M J Fettman, K L Mitchener, R A Hansen, K L Richardson, J A Walton, M A Scherk
JournalJournal of veterinary internal medicine (J Vet Intern Med) 2000 Sep-Oct Vol. 14 Issue 5 Pg. 503-6 ISSN: 0891-6640 [Print] United States
PMID11012113 (Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Orosomucoid
Topics
  • Animals
  • Carcinoma (blood, pathology, veterinary)
  • Carcinoma, Small Cell (blood, pathology, veterinary)
  • Cat Diseases (blood, pathology)
  • Cats (blood)
  • Immunodiffusion (veterinary)
  • Orosomucoid (analysis)
  • Regression Analysis
  • Sarcoma (blood, pathology, veterinary)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: