[Clinical study of cerebral blood flow in bilateral chronic subdural hematoma measured by 99mTc-HMPAO SPECT].

Abstract

Cerebral blood flow(CBF) in 34 patients with bilateral chronic subdural hematoma was measured by 99mTc-HMPAO SPECT before operation. The regional CBF was measured in 26 regions of the 10 cortical regions, putamen, thalamus and cerebellar hemisphere on both sides. According to the thickness of subdural hematoma, the thicker hematoma side was measured and examined as the thick hematoma side, and the other side as the thin hematoma side. Thirty four cases with bilateral chronic subdural hematoma were classified into four groups on the basis of clinical symptoms: 13 cases with headache(headache group), 10 cases with hemiparesis(hemiparesis group), 5 cases with tetraparesis(tetraparesis group) and 6 cases with consciousness disturbance or dementia(consciousness disturbance group), and into two groups according to the degree of midline brain shift on MRI: 14 cases of non-shifted group and 20 cases of shifted group. The average CBF of 34 patients in each region indicated a regional CBF reduction in the frontal, parietal and occipital cortices on the thin hematoma side, and in the putamen on the thick hematoma side. In the headache group, the regional CBF reduction on the thin hematoma side was found in the frontal, parietal and occipital cortices compared with the corresponding regions on the thick hematoma side, and in thalamus on the thick hematoma side. In the hemiparesis and tetraparesis groups, there was no statistically significant CBF reduction between the thick and thin hematoma sides. In the consciousness disturbance group, the CBF reduction in whole brain was remarkably significant. By the degree of the midline brain shift, the CBF reductions between the thick and thin hematoma sides were observed. Namely, in the shifted group, the CBF reductions were noted in the frontal, parietal and occipital cortices in the thin hematoma side, and in the putamen in the thick hematoma side. We concluded that the CBF reduction of bilateral chronic subdural hematoma was bilaterally found in the hemiparesis and tetraparesis groups, and which was finally observed in whole brain in the consciousness disturbance group.

• Authors: T Okuyama, K Saito, K Fukuyama, K Yamamoto, M Morimoto, T Aburano
• Journal: No to shinkei = Brain and nerve (No To Shinkei) Vol. 52 Issue 8 Pg. 709-14 (Aug 2000) ISSN: 0006-8969 [Print] Japan
• PMID: 11002481 (Publication Type: Journal Article)

Chemical References

• Technetium Tc 99m Exametazime

Topics

• Adult
• Aged
• Aged, 80 and over
• Blood Volume
• Cerebral Cortex (blood supply)
• Cerebrovascular Circulation (physiology)
• Chronic Disease
• Consciousness Disorders (diagnostic imaging)
• Female
• Headache (diagnostic imaging)
• Hematoma, Subdural (diagnostic imaging, physiopathology)
• Hemiplegia (diagnostic imaging)
• Humans
• Male
• Middle Aged
• Quadriplegia (diagnostic imaging)
• Radionuclide Imaging
• Regional Blood Flow
• Technetium Tc 99m Exametazime