| Abstract | Sensorineural hearing loss (SHL) of autoimmune origin is characterized by a rapidly progressive onset. Diagnosis is difficult and the condition responds to corticoids or immunosuppressant agents. Two cases with an onset over weeks and progressive hearing loss are reported. Both patients had SHL associated with another autoimmune disease. Laboratory findings were abnormal (immunoglobulins and lymphocyte populations), suggesting an immune disorder. Treatment with 1 mg/kg/day of deflazacort restored hearing to normal. Both patients are currently asymptomatic. The clinical and laboratory response of patients to deflazacort supported the diagnosis of autoimmune SHL. |
| Authors | J L Castillo, J A López-Escámez
(Affiliation: Servicio de ORL, Hospital La Inmaculada, Huércal-Overa, Almería.)
|
| Journal | Acta otorrinolaringológica española
(Acta Otorrinolaringol Esp)
2000 Jun-Jul
Vol. 51
Issue 5
Pg. 433-6
ISSN: 0001-6519 SPAIN |
| Vernacular Title | Diagnóstico y tratamiento de la hipoacusia neurosensorial de origen autoinmune. |
| PMID | 11000687
(Publication Type: Case Reports, English Abstract, Journal Article)
|
| Chemical References |
- Anti-Inflammatory Agents
- Pregnenediones
- deflazacort
|
| Topics |
- Adult
- Anti-Inflammatory Agents
(therapeutic use)
- Autoimmune Diseases
(complications)
- Disease Progression
- Hearing Loss, Sensorineural
(diagnosis, drug therapy, immunology)
- Humans
- Male
- Pregnenediones
(therapeutic use)
- Severity of Illness Index
|
