Abstract |
Conventional vaccines consist of a very large number of virtually identical molecules. While these have been extremely effective for prevention against viral diseases, development of vaccines against rapidly changing pathogens such as human immunodeficiency virus (HIV) and hepatitis C virus has proved to be more difficult. We propose a new approach to vaccination against these rapidly mutating pathogens by the use of vaccines consisting of a set of highly polymorphic recombinant molecules.
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Authors | J I Cohen |
Journal | Medical hypotheses
(Med Hypotheses)
Vol. 55
Issue 4
Pg. 353-5
(Oct 2000)
ISSN: 0306-9877 [Print] United States |
PMID | 11000067
(Publication Type: Journal Article)
|
Copyright | Copyright 2000 Harcourt Publishers Ltd. |
Chemical References |
- AIDS Vaccines
- Vaccines, Synthetic
- Viral Hepatitis Vaccines
- Viral Vaccines
|
Topics |
- AIDS Vaccines
(genetics)
- HIV
(genetics, immunology)
- Hepatitis C
(genetics, immunology)
- Humans
- Models, Biological
- Polymorphism, Genetic
- RNA Viruses
(genetics, immunology)
- Vaccination
- Vaccines, Synthetic
(genetics)
- Viral Hepatitis Vaccines
(genetics)
- Viral Vaccines
(genetics)
|