Treatment of REM sleep behavior disorder with donepezil: a report of three cases.

Abstract

Three patients with REM behavior disorder whose nocturnal symptoms were markedly improved by treatment with the acetylcholinesterase inhibitor donepezil are reported. Donepezil may have a role in the treatment of REM behavior disorder, possibly through its actions on cholinergic pathways in the brainstem.

• Authors: J M Ringman, J H Simmons
• Journal: Neurology (Neurology) Vol. 55 Issue 6 Pg. 870-1 (Sep 26 2000) ISSN: 0028-3878 [Print] United States
• PMID: 10994012 (Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, P.H.S.)

Chemical References

• Cholinesterase Inhibitors
• Indans
• Piperidines
• Donepezil

Topics

• Adult
• Aged
• Cholinesterase Inhibitors (therapeutic use)
• Donepezil
• Humans
• Indans (therapeutic use)
• Male
• Middle Aged
• Piperidines (therapeutic use)
• Polysomnography
• REM Sleep Behavior Disorder (drug therapy, physiopathology)