[Chemotherapy in colorectal carcinoma. From "one-drug-show" to therapeutic multiplicity].

Abstract

Over the past decade, the chemotherapeutic options in the treatment of colorectal carcinoma have improved considerably. Up into the nineties, chemotherapy for this condition was purely a "one-drug show", while, today, a range of effective substances and combinations are available, and these have considerably improved the prognosis of this tumour entity. Both the first and second line treatments are today firmly established. Determination of the most appropriate sequence and combination of these new drugs (primary combination therapy, sequential administration of the substances, etc.) is the subject of ongoing and planned future studies.

• Authors: W Köster, M Stahl, H Wilke
• Journal: MMW Fortschritte der Medizin (MMW Fortschr Med) Vol. 142 Issue 31-32 Pg. 30-2 (Aug 10 2000) ISSN: 1438-3276 [Print] Germany
• Vernacular Title: Chemotherapie beim kolorektalen Karzinom. Von der "One-drug-Show" zur therapeutischen Vielfalt.
• PMID: 10992764 (Publication Type: English Abstract, Journal Article)

Topics

• Antineoplastic Combined Chemotherapy Protocols (adverse effects, therapeutic use)
• Chemotherapy, Adjuvant
• Colorectal Neoplasms (drug therapy, pathology, surgery)
• Drug Administration Schedule
• Humans
• Neoplasm Staging