[The immunomodulating properties of translam].

Abstract

Effect of translam--beta-1,3;1,6-D-glucan on some of naturally occurring host protective mechanisms was investigated. It was shown that translam has potent biological activity: it has preventive effect on experimental bacterial infections, it stimulates absorbtion and digestion activity of mononuclear phagocytes, it effects on humoral and cell immunity. Translam had mitogenic activity.

• Authors: L A Ivanushko, N N Besednova, T S Zaporozhets, T N Zviagintseva
• Journal: Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] (Antibiot Khimioter) Vol. 45 Issue 7 Pg. 6-9 ( 2000) ISSN: 0235-2990 [Print] Russia (Federation)
• Vernacular Title: Immunomoduliruiushchie svoĭstva translama.
• PMID: 10987100 (Publication Type: English Abstract, Journal Article)

Chemical References

• Adjuvants, Immunologic
• Glucans
• Mitogens
• epiglucan

Topics

• Adjuvants, Immunologic (pharmacology, therapeutic use)
• Animals
• Antibody Formation (drug effects)
• Cells, Cultured
• Drug Evaluation, Preclinical
• Escherichia coli Infections (drug therapy, mortality)
• Glucans (pharmacology, therapeutic use)
• Guinea Pigs
• Immunity, Cellular (drug effects)
• Laminaria
• Macrophages (drug effects, immunology)
• Mice
• Mice, Inbred C57BL
• Mice, Inbred CBA
• Mitogens (pharmacology)
• Spleen (cytology, drug effects, immunology)
• Yersinia pseudotuberculosis Infections (drug therapy, mortality)