HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Periodic lateralized epileptiform discharges: association with seizures.

Abstract
The clinical features and EEGs of 45 consecutive patients (40 adults and 5 children) who had periodic lateralized epileptiform discharges (PLEDs) were reviewed to determine the relationship between seizures and PLEDs. Focal encephalitis and ischemic stroke were the most frequent underlying processes for adult patients. All of the children, but only six of the adults, had long-lasting cerebral disorders whereas the remaining adults had acute or subacute illness. There were 38 patients (84.4%) experiencing a seizure disorder. Twenty-six of them had their first seizure during their acute illness, as the pattern of PLED was encountered. Eight cases had status epilepticus, and seven of them had epilepsia partialis continua. Nineteen patients had a recent seizure in the day when PLEDs were observed but not during EEG recording; 12 patients had their seizures within 10 days before the observation of PLED. PLEDs were grouped into three categories with respect to their extensions: lateralized to one hemisphere (n = 22), localized in one region (n = 17) and being prominent over one side with contralateral spread (n = 6). The last group was found to be more closely associated with frequent seizures or status epilepticus than the other two groups. Our results showed that PLEDs were highly correlated with recent seizures in the majority of the patients. These EEG findings may be considered as a manifestation of an increased neuronal excitability caused by different etiologies; but not an ictal pattern.
AuthorsB Baykan, D Kinay, A Gökyigit, C Gürses
JournalSeizure (Seizure) Vol. 9 Issue 6 Pg. 402-6 (Sep 2000) ISSN: 1059-1311 [Print] England
PMID10985996 (Publication Type: Journal Article)
CopyrightCopyright 2000 BEA Trading Ltd.
Topics
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Central Nervous System Infections (complications)
  • Cerebrovascular Disorders (complications)
  • Child
  • Child, Preschool
  • Electroencephalography
  • Female
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Retrospective Studies
  • Seizures (diagnosis, etiology, physiopathology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: