Abstract | BACKGROUND: CASE: A 56-year-old woman had severe leukocytosis (>50 x 10(3)/microl) and fever without evidence of infection after radical hysterectomy for treatment of her cervical cancer. The parametrial recurrent mass appeared after the operation and exhibited extremely aggressive growth. Serum levels of G-CSF and IL-6 were extremely high, and immunohistochemical analysis and RT-PCR assays revealed that G-CSF and IL-6 as well as their receptors were produced in tumor cells. CONCLUSIONS:
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Authors | S Kyo, T Kanaya, M Takakura, M Inoue |
Journal | Gynecologic oncology
(Gynecol Oncol)
Vol. 78
Issue 3 Pt 1
Pg. 383-7
(Sep 2000)
ISSN: 0090-8258 [Print] United States |
PMID | 10985899
(Publication Type: Case Reports, Journal Article)
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Copyright | Copyright 2000 Academic Press. |
Chemical References |
- Interleukin-6
- Granulocyte Colony-Stimulating Factor
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Topics |
- Carcinoma, Squamous Cell
(metabolism, pathology)
- Cell Division
(physiology)
- Female
- Granulocyte Colony-Stimulating Factor
(biosynthesis, blood, physiology)
- Humans
- Interleukin-6
(biosynthesis, blood, physiology)
- Leukocyte Count
- Middle Aged
- Uterine Cervical Neoplasms
(metabolism, pathology)
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