Occupational allergic airbone contact dermatitis and delayed bronchial asthma from epoxy resin revealed by bronchial provocation test.

Abstract

Diglycidyl ether of bisphenol A (DGEBA) epoxy resins belong to the most common causes of occupational allergic contact dermatitis. DGEBA has on rare occasions caused occupational asthma. Here we present a patient who first developed occupational allergic contact dermatitis (ACD) caused by a single accidental exposure to DGEBA. Then, on continued occupational exposure to DGEBA, the patient developed occupational asthma from DGEBA, in addition to ACD. A bronchial provocation test with DGEBA caused a 36% drop in the peak expiratory flow, reflecting a delayed type of occupational asthma. This bronchial provocation test caused a strong dermatitis of the exposed skin of the face, in accordance with airborne ACD from DGEBA.

• Authors: L Kanerva, T Estlander, H Keskinen, R Jolanki
• Journal: European journal of dermatology : EJD (Eur J Dermatol) Vol. 10 Issue 6 Pg. 475-7 (Aug 2000) ISSN: 1167-1122 [Print] France
• PMID: 10980474 (Publication Type: Case Reports, Journal Article)

Chemical References

• Air Pollutants, Occupational
• Benzhydryl Compounds
• Epoxy Compounds
• Epoxy Resins
• 2,2-bis(4-glycidyloxyphenyl)propane

Topics

• Adult
• Air Pollutants, Occupational (adverse effects)
• Asthma (chemically induced, pathology)
• Benzhydryl Compounds
• Bronchial Provocation Tests
• Dermatitis, Allergic Contact (etiology, pathology)
• Dermatitis, Occupational (etiology, pathology)
• Epoxy Compounds (adverse effects)
• Epoxy Resins (adverse effects)
• Humans
• Hypersensitivity, Delayed (chemically induced, pathology)
• Male