[PLED pattern and its clinical significance in stroke patients].
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| Abstract |
The pathophysiological connection between periodic lateralized epileptiform discharges (PLED) and epileptic seizures is still not clear. In the study clinical data and EEG findings were analysed in 22 patients aged 43-90 years with a history of stroke in whom EEG disclosed PLED. Eleven patients were studied in the acute phase of stroke and 11 were studied years after stroke when the diagnosis was established of poststroke epilepsy. In 2 patients in acute stroke group single epileptic seizures occurred and 5 had partial status epilepticus. In the group with poststroke epilepsy 4 had single seizures and 4 had epileptic status with partial epilepsy seizures. Thus, in 15 out of 22 patients PLEDs were noted after epileptic seizures. In all cases PLED appearance was connected with consciousness disturbances, lasting 1 to 17 days. In 6 cases PLED pattern was interrupted by seizure activity over one hemisphere, in 3 of them partial epileptic seizures were associated with it. In acute phase of stroke neuroimaging demonstrated the presence of fresh ischaemic foci, but in cases of poststroke epilepsy no such fresh foci were observed. These results suggest that PLED frequently can be associated with epilepsy, and in some patients it can be a bioelectrical manifestation of partial status epileptic.
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| Authors | K Niedzielska, W Kuran, M Barańska-Gieruszczak, A Romaniak, M Rzeski, R Poniatowska, A Karliński, S Zamysłowski, J Lecka |
| Journal | Neurologia i neurochirurgia polska (Neurol Neurochir Pol) 2000 May-Jun Vol. 34 Issue 3 Pg. 467-74 ISSN: 0028-3843 [Print] Poland |
| Vernacular Title | Zmiany w eeg typu PLED i ich kliniczne znaczenie u chorych z udarem mózgu. |
| PMID | 10979541 (Publication Type: English Abstract, Journal Article) |
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