[Bacterial infection in the conjunctiva of patients with adenoviral conjunctivitis].

Abstract

PURPOSE:

We evaluate the microbiological features of mixed infection in adenovirus-infected conjunctiva.

SUBJECTS:

Isolation of bacteria was performed in 82 samples of adenoviral conjunctivitis at six eye clinics in Japan.

METHODS:

For microbiological diagnosis, we performed immunochromatography (IC) and polymerase chain reaction--restriction fragment length polymorphism (PCR-RFLP) analysis for detection and serotyping of adenovirus, and PCR for detection of herpes simplex virus (HSV) and Chlamydia trachomatis antigens out of 82 samples with adenoviral conjunctivitis.

RESULTS:

Pathogenic bacteria were isolated in 6 samples out of 82. Out of these 6 cases, 5 samples were gram-negative rods and most of them were Flavobacterium meningosepticum (4 samples). Adenovirus type 8 was isolated from all these mixed infection cases. However, HSV-1 and Chlamydia trachomatis were not found.

CONCLUSIONS:

From these results, it is suggested that gram-negative rods, especially F. meningosepticum, are the most common bacteria causing mixed bacterial infection in adenoviral conjunctivitis.

• Authors: Y Watanabe, E Uchio, N Itoh, N Usui, H Nakagawa, K Inoue, R Hinokuma, Y Asato, K Aoki, S Ohno
• Journal: Nippon Ganka Gakkai zasshi (Nippon Ganka Gakkai Zasshi) Vol. 104 Issue 8 Pg. 555-8 (Aug 2000) ISSN: 0029-0203 [Print] Japan
• PMID: 10979295 (Publication Type: English Abstract, Journal Article)

Topics

• Adenovirus Infections, Human (complications)
• Chlamydia Infections (complications)
• Chlamydia trachomatis
• Conjunctivitis (complications)
• Flavobacterium
• Gram-Negative Bacterial Infections (complications)
• Humans