Abstract |
Disorders in erythro- and immunopoiesis were studied in B6D2F1 mice with immunodeficiency induced by graft versus host reaction and with immunocomplex glomerulonephritis. By the 6th-7th months of the disease the animals developed anemia accompanied by enhanced phagocytic activity of macrophages and production of tumor necrosis factor. Macrophage dysfunction is presumed to be a cause of anemia.
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Authors | T G Sukhenko, O P Kolesnikova, V A Kozlov |
Journal | Bulletin of experimental biology and medicine
(Bull Exp Biol Med)
Vol. 129
Issue 4
Pg. 377-9
(Apr 2000)
ISSN: 0007-4888 [Print] United States |
PMID | 10977926
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Animals
- Antigen-Antibody Complex
(immunology)
- Erythropoiesis
- Glomerulonephritis
(immunology)
- Graft vs Host Disease
(immunology, physiopathology)
- Immunosuppression Therapy
- Leukopoiesis
- Mice
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