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Combined disorders in erythro- and immunopoiesis in (C57Bl/6xDBA/2)F1 mice with immunodeficiency induced by graft-versus-host reaction and immunocomplex glomerulonephritis.

Abstract
Disorders in erythro- and immunopoiesis were studied in B6D2F1 mice with immunodeficiency induced by graft versus host reaction and with immunocomplex glomerulonephritis. By the 6th-7th months of the disease the animals developed anemia accompanied by enhanced phagocytic activity of macrophages and production of tumor necrosis factor. Macrophage dysfunction is presumed to be a cause of anemia.
AuthorsT G Sukhenko, O P Kolesnikova, V A Kozlov
JournalBulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 129 Issue 4 Pg. 377-9 (Apr 2000) ISSN: 0007-4888 [Print] United States
PMID10977926 (Publication Type: Journal Article)
Chemical References
  • Antigen-Antibody Complex
Topics
  • Animals
  • Antigen-Antibody Complex (immunology)
  • Erythropoiesis
  • Glomerulonephritis (immunology)
  • Graft vs Host Disease (immunology, physiopathology)
  • Immunosuppression Therapy
  • Leukopoiesis
  • Mice

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