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Double-blind controlled crossover high-dose study of Azaribine in psoriasis.

Abstract
Azaribine used in high doses of 200 mg/kg a day is an effective agent in inducing temporary remissions in patients with severe psoriasis but potentially serious neurotoxicity may occur. Therapy should be initiated at lower doses of 125 mg/kg a day and advanced carefully only if clinical response does not ensue at the lower level.
AuthorsW A Crutcher, S L Moschella
JournalThe British journal of dermatology (Br J Dermatol) Vol. 92 Issue 2 Pg. 199-205 (Feb 1975) ISSN: 0007-0963 [Print] England
PMID1096923 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Placebos
  • Azauridine
Topics
  • Adult
  • Azauridine (administration & dosage, adverse effects, analogs & derivatives, therapeutic use)
  • Brain Diseases (chemically induced)
  • Clinical Trials as Topic
  • Electroencephalography
  • Female
  • Humans
  • Male
  • Middle Aged
  • Placebos
  • Psoriasis (drug therapy)

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