Hajdu-Cheney syndrome with growth hormone deficiency and neuropathy.

Abstract

A Hajdu-Cheney syndrome is a very rare congenital dysplastic bone disease including acro-osteolysis, short stature, characteristic facies, osteopenia, abnormalities of spine, skull and long bones. A 9 year-old boy presented at our clinic with a chief complaint of short stature and frequent lower respiratory tract infections. He had typical physical and radiographic features of Hajdu-Cheney syndrome associated with growth hormone (GH) deficiency and peripheral motor neuropathy. To our knowledge, this is the first report describing GH deficiency and neuropathy in Hajdu-Cheney syndrome.

• Authors: Z Siklar, G Tanyer, Y Dallar, F G Aksoy
• Journal: Journal of pediatric endocrinology & metabolism : JPEM (J Pediatr Endocrinol Metab) 2000 Jul-Aug Vol. 13 Issue 7 Pg. 951-4 ISSN: 0334-018X [Print] Germany
• PMID: 10968485 (Publication Type: Case Reports, Journal Article)

Chemical References

• Growth Hormone

Topics

• Absorptiometry, Photon
• Growth Hormone (deficiency)
• Humans
• Male
• Motor Neurons (pathology)
• Osteolysis, Essential (complications, physiopathology)
• Polyneuropathies (complications)