[Erythrocytosis post kidney transplantation and its pharmacological treatment: angiotensin converting enzyme inhibitors or angiotensin receptor blockers in a case].

Abstract

A 35 years old male is presented. Eight months after receiving a renal allograft his hypertension worsened and his packed red cell volume raised to 53.7% Enalapril was started and a 500 ml phlebotomy was performed. In three occasions packed red cell volumes decreased excessively and enalapril was discontinued. Finally, the drug was replaced with losartan, normalizing blood pressure values and stabilizing packed red cell volumes. This case illustrates the different reductions in packed red cell volumes induced by enalapril and losartan. These differences could have a therapeutic relevance.

• Authors: J Duclos
• Journal: Revista medica de Chile (Rev Med Chil) Vol. 128 Issue 2 Pg. 211-2 (Feb 2000) ISSN: 0034-9887 [Print] Chile
• Vernacular Title: Eritrocitosis post trasplante renal y su tratamiento farmacológico: inhibidores de la enzima convertidora de angiotensina versus bloqueadores de los receptores de angiotensina en un caso.
• PMID: 10962891 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Angiotensin-Converting Enzyme Inhibitors
• Enalapril
• Peptidyl-Dipeptidase A
• Losartan

Topics

• Adult
• Angiotensin-Converting Enzyme Inhibitors (adverse effects, therapeutic use)
• Enalapril (adverse effects, therapeutic use)
• Humans
• Kidney Transplantation
• Losartan (therapeutic use)
• Male
• Peptidyl-Dipeptidase A (therapeutic use)
• Polycythemia (drug therapy, etiology)