[Functional MR-pancreatography with secretin. A comparison of imaging quality and diagnostic value].

Abstract

PURPOSE:

The aim of the present study was to assess imaging improvement and diagnostic value of secretin stimulated MR-pancreatography (MRP) compared to conventional MRP.

MATERIALS AND METHODS:

50 patients were studied with a 1.0 T system using a single-shot-TSE sequence (RARE). Imaging quality and diameter of the different parts of the pancreatic tract and diagnoses were monitored before and after secretin.

RESULTS:

The visualization of the normal main pancreatic duct (MPD) was improved significantly in head, body and tail. Side branches were not depicted at all. Even in chronic pancreatitis a significant improvement of imaging quality could be observed, but only in patients without duct dilation before secretin. In advanced disease with duct dilation, secretin stimulation provided no further diagnostic improvement.

CONCLUSIONS:

In conclusion, secretin increases the diagnostic value of MRP especially in patients with normal or non-dilated native MPD and may help to avoid unnecessary invasive procedures such as ERCP.

• Authors: H Helmberger, K Hellerhoff, T Rüll, C Brandt, P Gerhardt
• Journal: RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin (Rofo) Vol. 172 Issue 4 Pg. 367-73 (Apr 2000) ISSN: 1438-9029 [Print] Germany
• Vernacular Title: Funktionelle MR-Pankreatikographie mit Sekretin--Intraindividueller Vergleich von Abbildungsqualität und Diagnoserelevanz.
• PMID: 10961222 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Contrast Media
• Gastrointestinal Agents
• Secretin

Topics

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Cholangiopancreatography, Endoscopic Retrograde
• Chronic Disease
• Contrast Media
• Data Interpretation, Statistical
• Diagnosis, Differential
• Evaluation Studies as Topic
• Female
• Gastrointestinal Agents
• Humans
• Magnetic Resonance Imaging (methods)
• Male
• Middle Aged
• Pancreatic Diseases (diagnosis, diagnostic imaging)
• Pancreatitis (diagnosis)
• Secretin