A preliminary investigation of remifentanil as a labor analgesic.

Abstract

IMPLICATIONS:

In this preliminary investigation, we evaluated the safety and analgesic efficacy of IV remifentanil for labor pain. Four women were studied, and then the trial was terminated because administration of this novel synthetic opioid produced significant maternal side effects in the absence of effective pain control.

• Authors: A J Olufolabi, J V Booth, H G Wakeling, P S Glass, D H Penning, J D Reynolds
• Journal: Anesthesia and analgesia (Anesth Analg) Vol. 91 Issue 3 Pg. 606-8 (Sep 2000) ISSN: 0003-2999 [Print] United States
• PMID: 10960385 (Publication Type: Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anesthetics, Intravenous
• Piperidines
• Remifentanil

Topics

• Adult
• Analgesia, Obstetrical (adverse effects)
• Anesthetics, Intravenous (administration & dosage, adverse effects)
• Female
• Humans
• Pain Measurement (drug effects)
• Piperidines (administration & dosage, adverse effects)
• Pregnancy
• Remifentanil
• Time Factors