HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Respiratory failure due to muscle weakness in inflammatory myopathies: maintenance therapy with home mechanical ventilation.

Abstract
Polymyositis and dermatomyositis are idiopathic inflammatory myopathies. Respiratory complications are a common feature, but ventilatory insufficiency is rare in these patients. We describe here three patients diagnosed with inflammatory myopathy (polymyositis) with respiratory failure due to muscle weakness who did not respond to immunosuppressive therapy. Mechanical ventilation at home with nasal or tracheal intermittent positive pressure resulted in improved chronic hypoventilation. This treatment improves the quality of life of patients with inflammatory myopathies and can be lifesaving in some cases.
AuthorsA Selva-O'Callaghan, L Sanchez-Sitjes, X Muñoz-Gall, T Mijares-Boeckh-Behrens, R Solans-Laque, J Angel Bosch-Gil, F Morell-Brotad, M Vilardell-Tarrés
JournalRheumatology (Oxford, England) (Rheumatology (Oxford)) Vol. 39 Issue 8 Pg. 914-6 (Aug 2000) ISSN: 1462-0324 [Print] England
PMID10952749 (Publication Type: Case Reports, Journal Article)
Topics
  • Administration, Inhalation
  • Adult
  • Female
  • Home Care Services
  • Humans
  • Male
  • Middle Aged
  • Muscle Weakness (complications)
  • Polymyositis (complications, therapy)
  • Positive-Pressure Respiration
  • Quality of Life
  • Respiration, Artificial
  • Respiratory Insufficiency (etiology, physiopathology, therapy)
  • Trachea

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: