Abstract |
In this study, 232 lactating dairy cows from six herds were observed for clinical signs of inflammation and simultaneously had blood samples drawn to determine whether or not Serum Amyloid A (SAA) was present. Serum protein electrophoresis and white blood cell differential count revealed inflammation in SAA+ samples but not in SAA-samples. Using positive SAA test results as the standard for presence of inflammation, clinical findings consistent with inflammation concurred with positive SAA results only 26% of the time (p<.001) while the lack of clinical signs consistent with inflammation concurred with negative SAA results 95% of the time (p<.001). There was also a significant difference (p<.005) in management styles in that cows permanently fed on wilted/cured forages and kept inside had a 26% prevalence of positive SAA blood samples whereas the overall prevalence of SAA+ samples was 16%. These findings indicate that whole herd screening using SAA can be of value to the veterinarian in helping to identify cows with inflammatory diseases. From a public health perspective, SAA testing of cows going to market can help differentiate those not needing intensive inspection from those that do.
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Authors | H J Karreman, G H Wentink, T Wensing |
Journal | The veterinary quarterly
(Vet Q)
Vol. 22
Issue 3
Pg. 175-8
(Jul 2000)
ISSN: 0165-2176 [Print] England |
PMID | 10952451
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Acute-Phase Reaction
(veterinary)
- Animals
- Cattle
- Cattle Diseases
(blood, diagnosis)
- Enzyme-Linked Immunosorbent Assay
- Female
- Inflammation
(blood, diagnosis, veterinary)
- Leukocyte Count
- Serum Amyloid A Protein
(analysis)
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