The effect of different commercial dentifrices on enamel lesion progression: an in vitro pH-cycling study.

Abstract

AIMS/OBJECTIVES:

To evaluate and compare the de/remineralization effects of dentifrices manufactured locally in some developing countries.

DESIGN:

Utilisation of the in vitro single-section and the pH-cycling model.

SETTING:

Laboratory. TEST MATERIALS: Dentifrices: Maxam DFP, Maxam Tartar Control, First, Tianqi Medicated from China; Vicco Vajradenti from India; Colgate MFP2, Crest Tartar Control from USA; and one non-fluoride dentifrice as control.

METHODS:

Sound molars were painted, leaving a 1 mm wide 'window' on the buccal and/or lingual surface and placed in a demineralisation solution for 96 h to produce artificial caries lesion approximately 80-100 mm deep. The teeth were then longitudinally sectioned (approximately 100 mm thick), and randomly divided into 8 groups (22 sections/group). The pH cycling model was utilised for 10 days.

OUTCOME MEASURES:

Polarised light microscopy and microradiography were used to evaluate the lesion progression before and after treatment.

RESULTS:

The control group showed an increase in lesion depth of 70 per cent and was statistically different from some test groups which ranged from -2 per cent to 68 per cent (P < 0.01, t-test). Statistically significant differences were also observed among some of the fluoride containing groups.

CONCLUSIONS:

This study suggests that, when compared to 'multinational dentifrices', Chinese and Indian dentifrices manufactured locally failed to show 'healing' efficacy even though they claimed to contain varying levels of fluoride.

• Authors: A Itthagarun, S H Wei, J S Wefel
• Journal: International dental journal (Int Dent J) Vol. 50 Issue 1 Pg. 21-8 (Feb 2000) ISSN: 0020-6539 [Print] England
• PMID: 10945176 (Publication Type: Comparative Study, Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Dentifrices
• Drugs, Chinese Herbal
• Fluorides

Topics

• China
• Dental Caries (pathology, therapy)
• Dental Enamel (pathology)
• Dentifrices (chemistry, therapeutic use)
• Developing Countries
• Drugs, Chinese Herbal
• Fluorides (administration & dosage)
• Humans
• Hydrogen-Ion Concentration
• India
• Microradiography
• Microscopy, Polarization
• Molar
• Random Allocation
• Tooth Demineralization
• Tooth Remineralization