Intravitreal antiviral injections as adjunctive therapy in the management of immunocompetent patients with necrotizing herpetic retinopathy.

Abstract

PURPOSE:

To report the use of intravitreal antiviral injections as adjunctive therapy in the management of three immunocompetent patients with necrotizing herpetic retinopathy.

METHOD:

Case series.

RESULTS:

Three patients with necrotizing herpetic retinopathy received intravitreal antiviral injections for treatment of progressive retinitis, despite standard intravenous acyclovir therapy. The retinitis resolved and visual acuity improved after a minimum of 6 months of follow-up in each case.

CONCLUSION:

Intravitreal antiviral injections may be a safe and efficacious adjunctive therapy in the management of patients with necrotizing herpetic retinopathy.

• Authors: K K Luu, I U Scott, N A Chaudhry, A Verm, J L Davis
• Journal: American journal of ophthalmology (Am J Ophthalmol) Vol. 129 Issue 6 Pg. 811-3 (Jun 2000) ISSN: 0002-9394 [Print] United States
• PMID: 10926999 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antiviral Agents
• Ganciclovir
• Acyclovir

Topics

• Acyclovir (therapeutic use)
• Adult
• Antiviral Agents (therapeutic use)
• Chemotherapy, Adjuvant
• Drug Therapy, Combination
• Eye Infections, Viral (drug therapy, immunology, virology)
• Female
• Ganciclovir (therapeutic use)
• Herpes Simplex (drug therapy, immunology, virology)
• Humans
• Immunocompetence
• Injections
• Male
• Middle Aged
• Retinal Necrosis Syndrome, Acute (drug therapy, immunology, virology)
• Visual Acuity
• Vitreous Body