Abstract | AIMS: To evaluate whether amniotic membrane transplantation can be an effective alternative treatment for neurotrophic corneal ulcers. METHODS: RESULTS: During a mean follow up period of 18.8 (SD 13.0) months, one to three layers of amniotic membrane with or without additional membrane as a patch were used for 17 procedures in 16 eyes for persistent neurotrophic corneal ulcers. All but four (76.4%) instances of amniotic membrane transplantation achieved rapid epithelialisation in 16.6 (9.0) days. Of the four eyes showing delayed healing, three eyes healed by tarsorrhaphy, and the remaining one eye with corneal perforation required penetrating keratoplasty and tarsorrhaphy. Two eyes gained vision better than 20/200. The healed corneal surface was accompanied by reduced inflammation. CONCLUSION: Amniotic membrane transplantation can be considered an effective alternative for treating severe neurotrophic corneal ulcers.
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Authors | H J Chen, R T Pires, S C Tseng |
Journal | The British journal of ophthalmology
(Br J Ophthalmol)
Vol. 84
Issue 8
Pg. 826-33
(Aug 2000)
ISSN: 0007-1161 [Print] England |
PMID | 10906085
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Amnion
(transplantation)
- Child, Preschool
- Corneal Ulcer
(surgery)
- Female
- Follow-Up Studies
- Humans
- Male
- Middle Aged
- Postoperative Care
(methods)
- Treatment Outcome
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