[Luteal insufficiency and benign breast diseases. Study in the light of data from the combined LH-RH + TRH test together with the study of ovarian steroids].

Abstract

Luteal deficiency has been attributed a patho-physiologic role in benign fibro-cystic breast disease, whereas Prolactin would not be involved in this disease. To tes these hypotheses, patients with fibro-cystic breast disease have been investigated through the combined LH-RH + TRH test, coupled with ovarian steroids estimations. 63 menstruating patients with ovulatory cycles, as evidenced by the temperature curve and proven fibro-cystic breast disease, as demonstrated by senography and thermogrphy and/or operation, have been selected for this study. The findings do not favour the role of luteal dificiency but rather the role of PRL hyperactivity in the pathol-physiology of fibro-cySTIC BREAST DISEASE.

• Authors: S Geller, J Grenier, K Nahoul, R Scholler
• Journal: Annales d'endocrinologie (Ann Endocrinol (Paris)) 1979 Jan-Feb Vol. 40 Issue 1 Pg. 45-6 ISSN: 0003-4266 [Print] France
• Vernacular Title: Insuffisance lutéale et mastopathies bénignes. Etude à la lumière des données de l'épreuve combinée LH-RH + TRH couplée à l'étude des stéroïdes ovariens.
• PMID: 109032 (Publication Type: English Abstract, Journal Article)

Chemical References

• Estrogens
• Gonadotropin-Releasing Hormone
• Testosterone
• Progesterone
• Thyrotropin-Releasing Hormone
• Luteinizing Hormone
• Follicle Stimulating Hormone

Topics

• Breast Diseases (etiology, physiopathology)
• Estrogens (blood)
• Female
• Follicle Stimulating Hormone (blood)
• Gonadotropin-Releasing Hormone
• Humans
• Luteinizing Hormone (blood)
• Menstruation Disturbances (complications)
• Progesterone (blood)
• Radioimmunoassay
• Testosterone (blood)
• Thyrotropin-Releasing Hormone