HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Randomised trial of safety and efficacy of postoperative enteral feeding in patients with severe pancreatitis: preliminary report.

AbstractOBJECTIVE:
To find out whether postoperative enteral feeding is safe and effective in patients with severe pancreatitis.
DESIGN:
Prospective randomised trial.
SETTING:
Teaching hospital, Latvia.
SUBJECTS:
29 patients who had been operated on for severe pancreatitis.
INTERVENTIONS:
They were randomised to have either enteral nutrition and conventional intravenous fluids postoperatively (n = 11), or conventional intravenous fluids only (n = 18). 17 additional patients who had had major abdominal operations for other conditions were also given enteral nutrition and intravenous fluids and comprised the control group.
MAIN OUTCOME MEASURES:
Nutritional intake, duration of stay in intensive care (ICU) and hospital morbidity, mortality, and outcome.
RESULTS:
1 patient died of the 11 given enteral nutrition combined with conventional intravenous fluids, compared with 5/18 given fluids only. The pattern of bowel transit in the fed group did not differ from that in the control group.
CONCLUSION:
Postoperative enteral nutrition seems to be safe and effective in patients with severe pancreatitis and may improve survival. Our results suggest that enteral and parenteral nutrition may complement each other in seriously ill patients.
AuthorsG Pupelis, E Austrums, A Jansone, R Sprucs, H Wehbi
JournalThe European journal of surgery = Acta chirurgica (Eur J Surg) Vol. 166 Issue 5 Pg. 383-7 (May 2000) ISSN: 1102-4151 [Print] England
PMID10881949 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Topics
  • Acute Disease
  • Enteral Nutrition (adverse effects)
  • Female
  • Humans
  • Length of Stay
  • Male
  • Middle Aged
  • Pancreatitis (mortality, therapy)
  • Parenteral Nutrition
  • Postoperative Care
  • Prospective Studies
  • Survival Analysis

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: