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[The result of adjuvant chemotherapy of colorectal cancer]

AbstractIn 103 patients with colorectal cancer the efficacy of three schedules of chemotherapy using fluorouracil (FU), FU with doxorubicin, FU with levamizol (LEV) was studied up. The result of treatment in 3 and 5 years was compared with that in patients, to whom merely surgical treatment was performed. Most effective treatment was application of FU with LEV: the three-year survival index of patients had constituted 66.7%, five-year one--54.5% and in control group--46.8 and 41.3% accordingly. The adjuvant chemotherapy performance was most effective in cancer stage III and in nondifferentiated type of tumor.
AuthorsR D Shiian
JournalKlinichna khirurhiia / Ministerstvo okhorony zdorov'ia Ukraïny, Naukove tovarystvo khirurhiv Ukraïny (Klin Khir) Issue 4 Pg. 31-2 ( 2000) ISSN: 0023-2130 UKRAINE
Vernacular TitleRezultat ad'iuvantnoï khimioterapiï kolorektal'noho raku.
PMID10857338 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Antineoplastic Agents
Topics
  • Aged
  • Antineoplastic Agents (therapeutic use)
  • Chemotherapy, Adjuvant
  • Colorectal Neoplasms (drug therapy)
  • Dose-Response Relationship, Drug
  • Female
  • Humans
  • Male
  • Middle Aged