[Kidney ultrastructure in experimental lithiasis and nephrocalcinosis].

Abstract

An experimental electron-microscopic study of the kidneys was carried out in experimental oxamide nephrolithiasis in rabbits and hypervitaminosis D in rats. The most pronounced changes were revealed in the proximal and the distal convoluted tubules. It is suggested that cytosomes and lysosome-like bodies possibly participated in stone formation and nephrocalcinosis. It is supposed that they played an important role in the morphogenesis of nephrolithiasis man.

• Authors: V N Blagodarov
• Journal: Biulleten' eksperimental'noi biologii i meditsiny (Biull Eksp Biol Med) Vol. 81 Issue 4 Pg. 494-6 ( 1976) ISSN: 0365-9615 [Print] Russia (Federation)
• Vernacular Title: Ul'trastruktura pochek pri éksperimental'nom kamneobrazovanii i nefrokal'tsinoze
• PMID: 1084176 (Publication Type: English Abstract, Journal Article)

Chemical References

• Ergocalciferols
• Oxalates

Topics

• Animals
• Ergocalciferols
• Kidney (ultrastructure)
• Kidney Calculi (chemically induced, pathology)
• Male
• Nephrocalcinosis (chemically induced, pathology)
• Oxalates
• Rabbits
• Rats