Discrepancy between Ga-67 citrate and F-18 fluorodeoxyglucose positron emission tomographic scans in pulmonary infection.

Abstract

The authors describe a patient with the acquired immunodeficiency syndrome who had active pulmonary tuberculosis and was receiving anti-tuberculosis treatment. High-grade fever and a right-sided pleural effusion had recently developed. Results of a Ga-67 scan were negative for any focal infection in the chest. Fluorine-18 fluorodeoxyglucose positron emission tomography showed increased uptake in the right lower lung field, which correlated with the diagnosis of concomitant bacterial pneumonia. Anti-tuberculosis treatment can decrease the sensitivity of the Ga-67 scan and could have contributed to this discrepancy. The authors predict that the fluorine-18 fluorodeoxyglucose positron emission tomographic scan will play an important diagnostic role in the management of such a selected group of patients.

• Authors: G K Goswami, S Jana, J F Santiago, G Buyukdereli, S S Salem, S Heiba, H M Abdel-Dayem
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 25 Issue 6 Pg. 490-1 (Jun 2000) ISSN: 0363-9762 [Print] United States
• PMID: 10836710 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antitubercular Agents
• Citrates
• Gallium Radioisotopes
• Radiopharmaceuticals
• Fluorodeoxyglucose F18
• Gallium
• gallium citrate

Topics

• AIDS-Related Opportunistic Infections (diagnostic imaging, drug therapy)
• Antitubercular Agents (therapeutic use)
• Citrates
• Fluorodeoxyglucose F18
• Gallium
• Gallium Radioisotopes
• Humans
• Male
• Middle Aged
• Pleural Effusion (diagnostic imaging)
• Pneumonia, Bacterial (diagnostic imaging)
• Radiopharmaceuticals
• Tomography, Emission-Computed
• Tuberculosis, Pulmonary (drug therapy)