Staminolactones A and B and norstaminol A: three highly oxygenated staminane-type diterpenes from Orthosiphon stamineus.

Abstract

[formula: see text] Staminolactones A (1) and B (2) and norstaminol A (3), three highly oxygenated staminane-type diterpenes having mild cytotoxic activities against highly liver-metastatic colon 26-L5 carcinoma cells, were isolated from the aerial part of the Vietnamese medicinal plant Orthosiphon stamineus (Lamiaceae). Their structures were elucidated on the basis of the extensive spectral analyses.

• Authors: P Stampoulis, Y Tezuka, A H Banskota, K Q Tran, I Saiki, S Kadota
• Journal: Organic letters (Org Lett) Vol. 1 Issue 9 Pg. 1367-70 (Nov 04 1999) ISSN: 1523-7060 [Print] United States
• PMID: 10825984 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antineoplastic Agents
• Diterpenes
• norstaminol A
• staminolactone A
• staminolactone B
• Oxygen

Topics

• Antineoplastic Agents (chemistry, pharmacology)
• Colonic Neoplasms (pathology)
• Diterpenes (chemistry, pharmacology)
• Lamiaceae (chemistry)
• Liver Neoplasms (pathology, secondary)
• Molecular Structure
• Oxygen (chemistry)
• Spectrum Analysis
• Tumor Cells, Cultured