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Failure of azithromycin in treatment of Brill-Zinsser disease.

Abstract
Two patients suffering from Brill-Zinsser disease were treated with azithromycin, which did not prove effective. Rickettsia prowazekii, the agent causing Brill-Zinsser disease, cannot be treated with azithromycin. Both patients had epidemiological features consistent with and a clinical course typical of the disease. The diagnosis of Brill-Zinsser disease was serologically confirmed.
AuthorsD Turcinov, I Kuzman, B Herendić
JournalAntimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 44 Issue 6 Pg. 1737-8 (Jun 2000) ISSN: 0066-4804 [Print] United States
PMID10817744 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Azithromycin
Topics
  • Anti-Bacterial Agents (therapeutic use)
  • Azithromycin (therapeutic use)
  • Humans
  • Male
  • Middle Aged
  • Rickettsia prowazekii (drug effects)
  • Treatment Failure
  • Typhus, Epidemic Louse-Borne (drug therapy)

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